Personal Agent Glymphatic Clearance Aquaporin-4 Sleep Skill

Zero-dependency Nedergaard glymphatic brain clearance modeler, slow-wave sleep (SWS) interstitial volume expansion quantifier, and nocturnal sleep position optimizer.

Architecture

flowchart TD
    SleepArchitecture[SWS Minutes, REM Minutes, Total Duration] --> GlymphaticEngine[Glymphatic Convective Engine]
    PostureInput[Sleep Posture: Lateral vs. Supine vs. Prone] --> PostureEngine[Lee et al. Biomechanical Posture Modeler]
    PostureEngine --> FluxMultiplier[Convective Flux Multiplier: 0.70x to 1.25x]
    GlymphaticEngine & FluxMultiplier --> InterstitialExpansion[Interstitial Space Expansion: +64% During SWS]
    InterstitialExpansion --> AQP4Polarization[AQP4 Endfoot Channel Convective Flux]
    AQP4Polarization --> NMSCSOutput[Neuro-Metabolic Solute Clearance Score: NMSCS]

Quickstart

from client import PersonalAgentGlymphaticClearanceAquaporin4Sleep

agent = PersonalAgentGlymphaticClearanceAquaporin4Sleep()
res = agent.model_nocturnal_glymphatic_flux(slow_wave_sleep_minutes=90.0, sleep_position="lateral_right")
print(f"NMSCS: {res['neuro_metabolic_solute_clearance_score_nmscs']}/100 | Clearance: {res['glymphatic_clearance_tier']}")