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genpark-personal-agent-somatosensory-transcranial-magnetic-cortical-silent-period-csp-skill

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SUMMARY

Calculates single-pulse TMS cortical silent period (CSP) duration and MEP-normalized inhibition ratios for motor cortex GABAB-mediated intracortical inhibition assessment.

README.md

Cortical Silent Period (CSP) TMS Personal Agent Skill

License: Apache-2.0
Python: 3.8+
Zero Dependencies
Model Context Protocol
Production Ready

Deterministic, zero-mock personal agent micro-skill for calculating Transcranial Magnetic Stimulation (TMS) Cortical Silent Period Duration (ms) and MEP-Normalized Ratio to quantify motor cortex $\text{GABA}_B$ intracortical inhibition.

Architecture

flowchart TD
    A[Single Suprathreshold TMS Pulse @ 120% RMT] --> B[Evoke Motor Evoked Potential MEP on Active Target Muscle]
    B --> C[Measure Suppression Duration of Voluntary EMG]
    C --> D[Compute CSP Duration ms & CSP / MEP Ratio]
    D --> E[Classify Normal vs Focal Dystonia Disinhibition < 110 ms]

Quickstart

from client import CorticalSilentPeriodTMSClient

client = CorticalSilentPeriodTMSClient()
result = client.evaluate_csp(
    csp_duration_ms=165.0,
    mep_amplitude_mv=3.8,
    stimulus_intensity_pct_rmt=120.0
)
print(result)

License

Apache-2.0

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