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genpark-personal-agent-cutaneous-microdialysis-perfusion-recovery-skill

mcp
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SUMMARY

Deterministic personal agent skill for calculating Cutaneous Microdialysis zero-net-flux (ZNF) in vivo extraction fraction and interstitial concentration.

README.md

Cutaneous Microdialysis Perfusion Recovery Skill

License
Python
OpenClaw
GenPark
MCP

Cutaneous Microdialysis In Vivo Relative Recovery and Zero-Net-Flux (ZNF) Quantitative Analyzer based on Bungay transport modeling.

flowchart TD
    A[Variable Perfusate Concentrations C_in] --> B[Collect Dialysate Concentrations C_out]
    B --> C[Compute Net Membrane Flux: Delta C = C_in - C_out]
    C --> D[Linear Regression: Delta C vs C_in]
    D --> E[Zero-Net-Flux Point: Delta C = 0 -> True C_interstitial]
    D --> F[Slope = In Vivo Probe Extraction Fraction E_d]
    E & F --> G[Biomarker Quantitation & Probe Delivery Guidance]

Features

  • Zero PIP Dependencies: Implemented strictly with Python Standard Library (math, json, sys, typing).
  • Zero-Net-Flux Method: Determines exact interstitial concentrations independent of unknown tissue tortuosity or probe fouling.
  • Bungay Transport Physics: Validated against classic in vivo microdialysis mass-transfer equations.
  • Dual Architecture: Native Python import and Model Context Protocol (MCP) JSON-RPC 2.0 stdio server.

Quickstart

python example_usage.py

License

Apache-2.0

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