Renal Fractional Excretion of Sodium (FeNa) & Urea Skill

Renal Fractional Excretion of Sodium (FeNa) & Urea (FeUrea) Quantitative Evaluator. Differentiates systemic hypovolemia from intrinsic tubular injury with diuretic compensation.

flowchart TD
    A[Serum & Urine Chemistries: Na, Cr, Urea] --> B{Diuretic Therapy Active?}
    B -- No --> C[Compute FeNa = U_Na * P_Cr / P_Na * U_Cr * 100%]
    B -- Yes --> D[Compute FeUrea = U_Urea * P_Cr / P_Urea * U_Cr * 100%]
    C --> E{FeNa Threshold}
    E -- < 1.0% --> F[Prerenal Hypoperfusion / Dehydration]
    E -- > 2.0% --> G[Intrinsic Acute Tubular Necrosis]
    D --> H{FeUrea Threshold}
    H -- < 35% --> F
    H -- > 50% --> G

Features

• Zero PIP Dependencies: Implemented strictly with Python Standard Library (math, json, sys, typing).
• Diuretic Compensation: Automatically switches to FeUrea when diuretics confound urinary sodium handling.
• Precision Nephrology: Quantitative clearance formulas matching clinical nephrology guidelines.
• Dual Architecture: Native Python import and Model Context Protocol (MCP) JSON-RPC 2.0 stdio server.

Quickstart

python example_usage.py

License

Apache-2.0